Article
A mitotic role for GSK-3beta kinase in Drosophila.
Cell cycle (Georgetown, Tex.) - 1 Dec 2008
Wojcik Edward J
Abstract excerpt
Glycogen synthase kinase-3beta (GSK-3beta) is involved in a wide variety of cellular processes, and implicated in a growing list of human diseases. Recent drug inhibition studies have suggested a role for GSK-3beta in mitosis in animals. Here, we take an alternative approach to understanding GSK-3beta function in mitosis by genetic mutational analysis in Drosophila. GSK-3beta function is well conserved between...
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