Article
A novel role for the CBF3 kinetochore-scaffold complex in regulating septin dynamics and cytokinesis.
The Journal of cell biology - 5 Dec 2005
Gillis Amethyst N, Thomas Scott, Hansen Scott D, Kaplan Kenneth B
Abstract excerpt
In budding yeast, the kinetochore scaffold complex centromere binding factor 3 (CBF3) is required to form kinetochores on centromere DNA and to allow proper chromosome segregation. We have previously shown that SKP1 and SGT1 balance the assembly and turnover of CBF3 complexes, a cycle that we suggest is independent of its role in chromosome segregation (Rodrigo-Brenni, M.C., S. Thomas, D.C. Bouck, and K.B....
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