Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Schizosaccharomyces pombe skp1+ encodes a protein kinase related to mammalian glycogen synthase kinase 3 and complements a cdc14 cytokinesis mutant.

Molecular and cellular biology - 1 Jan 1996

Plyte S E, Feoktistova A, Burke J D, Woodgett J R, Gould K L

Abstract excerpt

We report the cloning of the skp1+ gene, a Schizosaccharomyces pombe homolog of the glycogen synthase kinase 3 (GSK-3) family whose members in higher eukaryotes are involved in cell fate determination, nuclear signalling, and hormonal regulation. skp1 is 67% identical to mammalian GSK-3 beta and displays similar biochemical properties in vitro. Like GSK-3 beta, skp1 is phosphorylated on a conserved tyrosine...

Topics

Amino Acid Sequence
Animals
Base Sequence
Calcium-Calmodulin-Dependent Protein Kinases
Cell Cycle Proteins
Cell Division
Cloning, Molecular
DNA, Complementary
DNA, Fungal
Fungal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Deletion

Genes, Fungal

Genetic Complementation Test

Glycogen Synthase Kinase 3

Glycogen Synthase Kinases

Humans

Molecular Sequence Data

Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 8524294
DOI: 10.1128/MCB.16.1.179
PMCID: PMC230991

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8524294-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Schizosaccharomyces pombe skp1+ encodes a protein kinase related to mammalian glycogen synthase kinase 3 and complements a cdc14 cytokinesis mutant.PMID 8524294Read ↗

A Schizosaccharomyces pombe gene, ksg1, that shows structural homology to the human phosphoinositide-dependent protein kinase PDK1, is essential for growth, mating and sporulation.Semantic proximity Read ↗

Essential role for Schizosaccharomyces pombe pik1 in septation.Semantic proximity Read ↗

A cyclin-dependent kinase that promotes cytokinesis through modulating phosphorylation of the carboxy terminal domain of the RNA Pol II Rpb1p sub-unit.Semantic proximity Read ↗

Spm1, a stress-activated MAP kinase that regulates morphogenesis in S.pombe.Semantic proximity Read ↗

Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and division.Semantic proximity Read ↗

Mkp1 and Mkp2, two MAPKAP-kinase homologues in Schizosaccharomyces pombe, interact with the MAP kinase Sty1.Semantic proximity Read ↗

Schizosaccharomyces pombe Pak-related protein, Pak1p/Orb2p, phosphorylates myosin regulatory light chain to inhibit cytokinesis.Semantic proximity Read ↗

Identification of a novel casein kinase-1 homolog in fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Characterization of ypa1 and ypa2, the Schizosaccharomyces pombe orthologs of the peptidyl proyl isomerases that activate PP2A, reveals a role for Ypa2p in the regulation of cytokinesis.Semantic proximity Read ↗

Characterization of Ksg1 protein kinase-dependent phosphoproteome in the fission yeast S. pombe.Semantic proximity Read ↗

Genetic and molecular characterization of Skb15, a highly conserved inhibitor of the fission yeast PAK, Shk1.Semantic proximity Read ↗

Direct activation of the fission yeast PAK Shk1 by the novel SH3 domain protein, Skb5.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.