Article
Glycogen synthase kinase-3 is required for efficient Dictyostelium chemotaxis.
Molecular biology of the cell - 1 Aug 2010
Teo Regina, Lewis Kimberley J, Forde Josephine E, Ryves W Jonathan, Reddy Jonathan V, Rogers Benjamin J, Harwood Adrian J
Abstract excerpt
Glycogen synthase kinase-3 (GSK3) is a highly conserved protein kinase that is involved in several important cell signaling pathways and is associated with a range of medical conditions. Previous studies indicated a major role of the Dictyostelium homologue of GSK3 (gskA) in cell fate determination during morphogenesis of the fruiting body; however, transcriptomic and proteomic studies have suggested that GSK3...
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