Article
TRIM5α polymorphism identification in cynomolgus macaques of Vietnamese origin and Chinese rhesus macaques.
American journal of primatology - 1 Sept 2013
Zhang Guiqing, Qiu Wei, Xiang Ruirui, Ling Fei, Zhuo Min, Du Hongli, Wang Jufang, Wang Xiaoning
Abstract excerpt
TRIM5α is a retroviral restriction factor, in which the B30.2 (SPRY) and coiled-coil domains cooperate to determine the specificity of TRIM5α-mediated capture of retroviral capsids. Here, all exons of TRIM5α were analyzed in 39 Vietnamese cynomolgus macaques (VCE) and 29 Chinese rhesus macaques (CR). Our results revealed the presence of 22 alleles using the PHASE 2.0 software package (PHylogenetics And Sequence...
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