Article
The effects of TRIM5α polymorphism on HIV-2ROD and SIVmac239 replication in PBMCs from Chinese rhesus macaques and Vietnamese-origin cynomolgus macaques.
Virology - 1 Jan 2016
Zhang Hui-Ling, Liu Feng-Liang, Jin Ya-Bin, Deng Qing, Liu Bei-Lei, Zhuo Min, Liu Xiao-Hui, Zheng Yong-Tang, Ling Fei
Abstract excerpt
Because of the difficulty of obtaining Indian-origin rhesus macaques, Chinese-origin rhesus macaques (CR) and Vietnamese-origin cynomolgus macaques (CM) are now used frequently in HIV/AIDS research. Nonetheless, the effects of TRIM5α polymorphism on viral replication in both CR and CM are unclear. To address these questions, we recruited 70 unrelated CR and 40 unrelated CM and studied the effect of TRIM5α...
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