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Article

TRIM5 allelic polymorphism in macaque species/populations of different geographic origins: its impact on SIV vaccine studies.

Tissue antigens - 1 Oct 2011

de Groot N G, Heijmans C M C, Koopman G, Verschoor E J, Bogers W M, Bontrop R E

Abstract excerpt

Tripartite motif 5α (TRIM5α) is a potent antiretroviral immune factor present in the cytoplasm of cells of most tissue types. The rhesus macaque TRIM5 gene has been shown to display polymorphism, with different variants being divided into three groups (TRIM5(TFP), TRIM5(Q), and TRIM5(CypA)), which may have divergent retroviral effects on infection. Along with rhesus macaques, cynomolgus macaques are also used in...

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Source

Identifiers

PMID: 21929574
DOI: 10.1111/j.1399-0039.2011.01768.x

Genes

TRIM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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TRIM5 allelic polymorphism in macaque species/populations of different geographic origins: its impact on SIV vaccine studies.PMID 21929574Read ↗

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