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Article

All three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restriction.

Journal of virology - 1 Sept 2006

Ohkura Sadayuki, Yap Melvyn W, Sheldon Tom, Stoye Jonathan P

Abstract excerpt

Recent studies have revealed the contribution of TRIM5alpha to retrovirus restriction in cells from a variety of primate species. TRIM5alpha consists of a tripartite motif (the RBCC domain) followed by a B30.2 domain. The B30.2 domain is thought to be involved in determination of restriction specificity and contains three variable regions. To investigate the relationship between the phylogeny of primate...

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Identifiers

PMID: 16912305
DOI: 10.1128/JVI.00688-06
PMCID: PMC1563890

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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