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Article

The ligand binding domain of GCNF is not required for repression of pluripotency genes in mouse fetal ovarian germ cells.

PloS one - 1 Jan 2013

Okumura Leah M, Lesch Bluma J, Page David C

Abstract excerpt

In mice, successful development and reproduction require that all cells, including germ cells, transition from a pluripotent to a differentiated state. This transition is associated with silencing of the pluripotency genes Oct4 and Nanog. Interestingly, these genes are repressed at different developmental timepoints in germ and somatic cells. Ovarian germ cells maintain their expression until about embryonic day...

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Identifiers

PMID: 23762465
DOI: 10.1371/journal.pone.0066062
PMCID: PMC3676325

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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The ligand binding domain of GCNF is not required for repression of pluripotency genes in mouse fetal ovarian germ cells.PMID 23762465Read ↗

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