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Article

The aryl hydrocarbon receptor promotes differentiation during mouse preimplantational embryo development.

Stem cell reports - 14 Sept 2021

Nacarino-Palma Ana, González-Rico Francisco J, Rejano-Gordillo Claudia M, Ordiales-Talavero Ana, Merino Jaime M, Fernández-Salguero Pedro M

Abstract excerpt

Mammalian embryogenesis is a complex process controlled by transcription factors that regulate the balance between pluripotency and differentiation. Transcription factor aryl hydrocarbon receptor (AhR) regulates OCT4/POU5F1 and NANOG, both essential controllers of pluripotency, stemness and early embryo development. Molecular mechanisms controlling OCT4/POU5F1 and NANOG during embryogenesis remain unidentified....

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Source

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Identifiers

PMID: 34478649
DOI: 10.1016/j.stemcr.2021.08.002
PMCID: PMC8452532

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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