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Article

Follistatin Regulates Germ Cell Nest Breakdown and Primordial Follicle Formation

24 Nov 2010

Abstract excerpt

Follistatin (FST) is an antagonist of activin and related TGFβ superfamily members that has important reproductive actions as well as critical regulatory functions in other tissues and systems. FST is produced as three protein isoforms that differ in their biochemical properties and in their localization within the body. We created FST288-only mice that only express the short FST288 isoform and previously...

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PMID: 21106872
DOI: 10.1210/en.2010-0950

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