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Article

TAL effector nucleases induce mutations at a pre-selected location in the genome of primary barley transformants.

Plant molecular biology - 1 Oct 2013

Wendt Toni, Holm Preben Bach, Starker Colby G, Christian Michelle, Voytas Daniel F, Brinch-Pedersen Henrik, Holme Inger Bæksted

Abstract excerpt

Transcription activator-like effector nucleases (TALENs) enable targeted mutagenesis in a variety of organisms. The primary advantage of TALENs over other sequence-specific nucleases, namely zinc finger nucleases and meganucleases, lies in their ease of assembly, reliability of function, and their broad targeting range. Here we report the assembly of several TALENs for a specific genomic locus in barley. The...

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Identifiers

PMID: 23689819
DOI: 10.1007/s11103-013-0078-4
PMCID: PMC7880306

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Source receipt: pubmed, retrieved 7 Sept 2026.

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