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Article

Designing and testing the activities of TAL effector nucleases.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014

Lin Yanni, Cradick Thomas J, Bao Gang

Abstract excerpt

Transcription activator-like effector nucleases (TALENs) have rapidly developed into a powerful tool for genome editing. To avoid labor-intensive and time-consuming experimental screening for active TALENs, a scoring system can help select optimal target sites. Here we describe a procedure to design active TALENs using a scoring system named Scoring Algorithm for Predicted TALEN Activity (SAPTA) and a method to...

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PMID: 24557905
DOI: 10.1007/978-1-62703-761-7_13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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