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Article

Effect of APOE and CD33 on Cognitive Decline.

PloS one - 1 Jan 2015

Hayden Kathleen M, Lutz Michael W, Kuchibhatla Maragatha, Germain Cassandra, Plassman Brenda L

Abstract excerpt

OBJECTIVE: An Alzheimer's disease (AD) diagnosis is preceded by a long period of cognitive decline. We previously demonstrated increased risk of decline among individuals possessing one or more APOE ε4 alleles together with a family history of AD. The objective of this study is to investigate the possibility that such an increased risk might be due to AD risk genes with small effects in combination with APOE....

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Identifiers

PMID: 26102276
DOI: 10.1371/journal.pone.0130419
PMCID: PMC4478019

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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