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Article

Brain APOE expression quantitative trait loci-based association study identified one susceptibility locus for Alzheimer's disease by interacting with APOE ε4.

Scientific reports - 23 May 2018

Zhang Aiqian, Zhao Qingnan, Xu Dabao, Jiang Shan

Abstract excerpt

Some studies have demonstrated interactions of AD-risk single nucleotide polymorphisms (SNPs) in non-APOE regions with APOE genotype. Nevertheless, no study reported interactions of expression quantitative trait locus (eQTL) for APOE with APOE genotype. In present study, we included 9286 unrelated AD patients and 8479 normal controls from 12 cohorts of NIA Genetics of Alzheimer's Disease Data Storage Site...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29795290
DOI: 10.1038/s41598-018-26398-1
PMCID: PMC5966425

Genes

APOE

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