Article
Long-term home cage activity scans reveal lowered exploratory behaviour in symptomatic female Rett mice.
Behavioural brain research - 1 Aug 2013
Robinson Lianne, Plano Andrea, Cobb Stuart, Riedel Gernot
Abstract excerpt
Numerous experimental models have been developed to reiterate endophenotypes of Rett syndrome, a neurodevelopmental disorder with a multitude of motor, cognitive and vegetative symptoms. Here, female Mecp2(Stop) mice [1] were characterised at mild symptomatic conditions in tests for anxiety (open field, elevated plus maze) and home cage observation systems for food intake, locomotor activity and circadian...
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