Article
Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences.
Molecular endocrinology (Baltimore, Md.) - 1 Oct 2013
Stashi Erin, Wang Lei, Mani Shailaja K, York Brian, O'Malley Bert W
Abstract excerpt
Steroid receptor coactivators (SRCs) are important transcriptional modulators that regulate nuclear receptor and transcription factor activity to adjust transcriptional output to cellular demands. Highlighting their pleiotropic effects, dysfunction of the SRCs has been found in numerous pathologies including cancer, inflammation, and metabolic disorders. The SRC family is expressed strongly in the brain including...
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