Article
Breathing abnormalities in a female mouse model of Rett syndrome.
The journal of physiological sciences : JPS - 1 Sept 2015
Johnson Christopher M, Cui Ningren, Zhong Weiwei, Oginsky Max F, Jiang Chun
Abstract excerpt
Rett syndrome (RTT) is a female neurodevelopmental disease with breathing abnormalities. To understand whether breathing defects occur in the early lives of a group of female Mecp2(+/-) mice, a mouse model of RTT, and what percentage of mice shows RTT-like breathing abnormality, breathing activity was measured by plethysmography in conscious mice. Breathing frequency variation and central apnea in a group of...
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