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Article

Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome.

Human molecular genetics - 15 Jan 2005

Moretti Paolo, Bouwknecht J Adriaan, Teague Ryan, Paylor Richard, Zoghbi Huda Y

Abstract excerpt

Rett syndrome (RTT) is an autistic spectrum disorder with a known genetic basis. RTT is caused by loss of function mutations in the X-linked gene MECP2 and is characterized by loss of acquired motor, social and language skills in females beginning at 6-18 months of age. MECP2 mutations also cause...

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Source

Identifiers

PMID: 15548546
DOI: 10.1093/hmg/ddi016

Genes

MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15548546-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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