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Article

Molecular subtypes of glioma identified by genome-wide methylation profiling.

Genes, chromosomes & cancer - 1 Jul 2013

Kloosterhof Nanne K, de Rooi Johan J, Kros Max, Eilers Paul H C, Sillevis Smitt Peter A E, van den Bent Martin J, French Pim J

Abstract excerpt

Recent studies have indicated a prognostic role for genome-wide methylation in gliomas: Tumors that show an overall increase in DNA methylation at CpG sites (CIMP+; CpG island methylator phenotype) have a more favorable prognosis than CIMP- gliomas. Here, we have determined whether methylation profiling can identify more and clinically relevant molecular subtypes of glioma by performing genome-wide methylation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23629961
DOI: 10.1002/gcc.22062

Genes

EGFR
IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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