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Article

Glioma CpG island methylator phenotype (G-CIMP): biological and clinical implications.

Neuro-oncology - 9 Apr 2018

Malta Tathiane M, de Souza Camila F, Sabedot Thais S, Silva Tiago C, Mosella Maritza S, Kalkanis Steven N, Snyder James, Castro Ana Valeria B, Noushmehr Houtan

Abstract excerpt

Gliomas are a heterogeneous group of brain tumors with distinct biological and clinical properties. Despite advances in surgical techniques and clinical regimens, treatment of high-grade glioma remains challenging and carries dismal rates of therapeutic success and overall survival. Challenges include the molecular complexity of gliomas, as well as inconsistencies in histopathological grading, resulting in an...

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Identifiers

PMID: 29036500
DOI: 10.1093/neuonc/nox183
PMCID: PMC5892155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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