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Article

DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma.

Journal of the National Cancer Institute - 19 Jan 2011

Christensen Brock C, Smith Ashley A, Zheng Shichun, Koestler Devin C, Houseman E Andres, Marsit Carmen J, Wiemels Joseph L, Nelson Heather H, Karagas Margaret R, Wrensch Margaret R, Kelsey Karl T, Wiencke John K

Abstract excerpt

BACKGROUND: Although much is known about molecular and chromosomal characteristics that distinguish glioma histological subtypes, DNA methylation patterns of gliomas and their association with other tumor features such as mutation of isocitrate dehydrogenase (IDH) genes have only recently begun to be investigated. METHODS: DNA methylation of glioblastomas, astrocytomas, oligodendrogliomas, oligoastrocytomas,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21163902
DOI: 10.1093/jnci/djq497
PMCID: PMC3022619

Genes

IDH1
IDH2

Provenance

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