Article

Distinct epigenetic shift in a subset of Glioma CpG island methylator phenotype (G-CIMP) during tumor recurrence

2017-06-28

Abstract excerpt

<h4>SUMMARY</h4> Histomorphology and current grading schemes are unable to predict glioma relapse and malignant tumor progression. We reported that the IDH-mutant associated Glioma-CpG Island Methylator Phenotype (G-CIMP) can be further divided into two clinically distinct subtypes independent of histopathological grading (G-CIMP-high and -low) with evidence of correlation with tumor progression. Here we performe...

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Literature Corpus work: ee55b1f7-ab44-5662-9701-cab48f415eb4
DOI: 10.1101/156646

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