Article
Genome-wide association study of age at menarche in African-American women.
Human molecular genetics - 15 Aug 2013
Demerath Ellen W, Liu Ching-Ti, Franceschini Nora, Chen Gary, Palmer Julie R, Smith Erin N, Chen Christina T L, Ambrosone Christine B, Arnold Alice M, Bandera Elisa V, Berenson Gerald S, Bernstein Leslie, Britton Angela, Cappola Anne R, Carlson Christopher S, Chanock Stephen J, Chen Wei, Chen Zhao, Deming Sandra L, Elks Cathy E, Evans Michelle K, Gajdos Zofia, Henderson Brian E, Hu Jennifer J, Ingles Sue, John Esther M, Kerr Kathleen F, Kolonel Laurence N, Le Marchand Loic, Lu Xiaoning, Millikan Robert C, Musani Solomon K, Nock Nora L, North Kari, Nyante Sarah, Press Michael F, Rodriquez-Gil Jorge L, Ruiz-Narvaez Edward A, Schork Nicholas J, Srinivasan Sathanur R, Woods Nancy F, Zheng Wei, Ziegler Regina G, Zonderman Alan, Heiss Gerardo, Gwen Windham B, Wellons Melissa, Murray Sarah S, Nalls Michael, Pastinen Tomi, Rajkovic Aleksandar, Hirschhorn Joel, Adrienne Cupples L, Kooperberg Charles, Murabito Joanne M, Haiman Christopher A
Abstract excerpt
African-American (AA) women have earlier menarche on average than women of European ancestry (EA), and earlier menarche is a risk factor for obesity and type 2 diabetes among other chronic diseases. Identification of common genetic variants associated with age at menarche has a potential value in pointing to the genetic pathways underlying chronic disease risk, yet comprehensive genome-wide studies of age at...
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