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Article

The genetic architecture of age at menarche and its causal effects on other traits.

Journal of human genetics - 1 Dec 2024

Feng Gui-Juan, Xu Qian, Zhao Qi-Gang, Han Bai-Xue, Yan Shan-Shan, Zhu Jie, Pei Yu-Fang

Abstract excerpt

Age at menarche (AAM) is a sign of puberty of females. It is a heritable trait associated with various adult diseases. However, the genetic mechanism that determines AAM and links it to disease risk is poorly understood. Aiming to uncover the genetic basis for AAM, we conducted a joint association study in up to 438,089 women from 3 genome-wide association studies of European and East Asian ancestries. A series...

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Identifiers

PMID: 39147824
DOI: 10.1038/s10038-024-01287-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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