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Joint Genome-Wide Association Study Identifies Twenty-One Novel Loci for Age at Menarche and Highlights Its Causal Association with Other Complex Diseases

2021-10-11

Abstract excerpt

<title>Abstract</title> <p>Age at menarche (AAM) is a sign of puberty of females. It is a heritable trait associated with various adult diseases. However, the genetic mechanism that determines AAM and links it to disease risk is poorly understood. Aiming to uncover the genetic basis for AAM, we conducted a joint association study in up to 438,089 participants from 3 genome-wide association studies of European and...

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Literature Corpus work: adb4070c-92d2-5356-abc3-affe1c4728b3
DOI: 10.21203/rs.3.rs-955340/v1

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