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Article

Age at menarche and age at natural menopause in East Asian women: a genome-wide association study.

Age (Dordrecht, Netherlands) - 1 Dec 2016

Shi Jiajun, Zhang Ben, Choi Ji-Yeob, Gao Yu-Tang, Li Huaixing, Lu Wei, Long Jirong, Kang Daehee, Xiang Yong-Bing, Wen Wanqing, Park Sue K, Ye Xingwang, Noh Dong-Young, Zheng Ying, Wang Yiqin, Chung Seokang, Lin Xu, Cai Qiuyin, Shu Xiao-Ou

Abstract excerpt

Age at menarche (AM) and age at natural menopause (ANM) are complex traits with a high heritability. Abnormal timing of menarche or menopause is associated with a reduced span of fertility and risk for several age-related diseases including breast, endometrial and ovarian cancer, cardiovascular disease, and osteoporosis. To identify novel genetic loci for AM or ANM in East Asian women and to replicate previously...

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Identifiers

PMID: 27629107
DOI: 10.1007/s11357-016-9939-5
PMCID: PMC5266214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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