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Menarche-a journey into womanhood: age at menarche and health-related outcomes in East Asians.

Human reproduction (Oxford, England) - 3 Jun 2024

Chiou Jian-Shiun, Lin Ying-Ju, Chang Cherry Yin-Yi, Liang Wen-Miin, Liu Ting-Yuan, Yang Jai-Sing, Chou Chen-Hsing, Lu Hsing-Fang, Chiu Mu-Lin, Lin Ting-Hsu, Liao Chiu-Chu, Huang Shao-Mei, Chou I-Ching, Li Te-Mao, Huang Peng-Yan, Chien Tzu-Shun, Chen Hou-Ren, Tsai Fuu-Jen

Abstract excerpt

STUDY QUESTION: Are there associations of age at menarche (AAM) with health-related outcomes in East Asians? SUMMARY ANSWER: AAM is associated with osteoporosis, Type 2 diabetes (T2D), glaucoma, and uterine fibroids, as demonstrated through observational studies, polygenic risk scores, genetic correlations, and Mendelian randomization (MR), with additional findings indicating a causal effect of BMI and T2D on...

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PMID: 38527428
DOI: 10.1093/humrep/deae060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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