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Health outcomes of age at menarche in European women: a two-sample Mendelian randomization study

10 Jun 2023

Abstract excerpt

BACKGROUND: Observational studies have shown an association between age at menarche (AAM) and the risk of gynecological diseases. However, the causality cannot be determined due to residual confounding. METHODS: We conducted a Mendelian randomization (MR) study to evaluate the causal effect of AAM on several gynecological diseases, including endometriosis, female infertility, pre-eclampsia or eclampsia, uterine...

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PMID: 37302123
DOI: 10.1093/postmj/qgad023

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