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Article

Methylation-dependent and -independent genomic targeting principles of the MBD protein family.

Cell - 11 Apr 2013

Baubec Tuncay, Ivánek Robert, Lienert Florian, Schübeler Dirk

Abstract excerpt

To gain insight into the cellular readout of DNA methylation, we established a strategy for systematically profiling the genome-wide distribution of chromatin-interacting factors. This enabled us to create genomic maps for the methyl-CpG-binding domain (MBD) family of proteins, including disease-relevant mutants, deletions, and isoforms. In vivo binding of MBD proteins occurs predominantly as a linear function of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23582333
DOI: 10.1016/j.cell.2013.03.011

Genes

MBD2
MBD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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