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Article

Structure of tumor necrosis factor-alpha haploblocks in European populations.

Immunogenetics - 1 Jul 2013

Merino Aimee M, Zhang Kui, Kaslow Richard A, Aissani Brahim

Abstract excerpt

DNA variants in the tumor necrosis factor-α (TNF) and linked lymphotoxin-α genes, and specific alleles of the highly polymorphic human leukocyte antigen B (HLA-B) gene have been implicated in a plethora of immune and infectious diseases. However, the tight linkage disequilibrium characterizing the central region of the human major histocompatibility complex (MHC) containing these gene loci has made difficult the...

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Source

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Identifiers

PMID: 23579626
DOI: 10.1007/s00251-013-0700-2
PMCID: PMC3985396

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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