Article
High-Density SNP genotyping defines 17 distinct haplotypes of the TNF block in the Caucasian population: implications for haplotype tagging.
Human mutation - 1 Dec 2004
Allcock Richard J N, Windsor Lydia, Gut Ivo G, Kucharzak Ramon, Sobre Laetitia, Lechner Doris, Garnier Jean-Guillaume, Baltic Svetlana, Christiansen Frank T, Price Patricia
Abstract excerpt
The region spanning the tumor necrosis factor (TNF) cluster in the human major histocompatibility complex (MHC) has been implicated in susceptibility to numerous immunopathological diseases, including type 1 diabetes mellitus and rheumatoid arthritis. However, strong linkage disequilibrium across...
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