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Article

Complex haplotypic structure of the central MHC region flanking TNF in a West African population.

Genes and immunity - 1 Oct 2003

Ackerman H C, Ribas G, Jallow M, Mott R, Neville M, Sisay-Joof F, Pinder M, Campbell R D, Kwiatkowski D P

Abstract excerpt

TNF polymorphisms have been associated with susceptibility to malaria and other infectious and inflammatory conditions. We investigated a sample of 150 West African chromosomes to determine linkage disequilibrium (LD) between 25 SNP markers located in an 80 kb segment of the MHC Class III region encompassing TNF and eight neighbouring genes. We observed 45 haplotypes, and 22 of them comprise 80% of the sample....

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Source

Identifiers

PMID: 14551600
DOI: 10.1038/sj.gene.6364008

Genes

TNF
LTA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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