Article
Diversity of extended HLA-DRB1 haplotypes in the Finnish population.
PloS one - 1 Jan 2013
Wennerström Annika, Vlachopoulou Efthymia, Lahtela L Elisa, Paakkanen Riitta, Eronen Katja T, Seppänen Mikko, Lokki Marja-Liisa
Abstract excerpt
The Major Histocompatibility Complex (MHC, 6p21) codes for traditional HLA and other host response related genes. The polymorphic HLA-DRB1 gene in MHC Class II has been associated with several complex diseases. In this study we focus on MHC haplotype structures in the Finnish population. We explore the variability of extended HLA-DRB1 haplotypes in relation to the other traditional HLA genes and a selected group...
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