Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nucleotide polymorphism of the TNF gene cluster in six Chinese populations.

Journal of human genetics - 1 Jun 2010

Zhang Yongbiao, Zhang Feng, Lin Hongbin, Shi Lei, Wang Panpan, Shi Li, Gong Qiang, Li Xin, Wang Mei, Hu Songnian, Chu Jiayou, Wang Duen-Mei

Abstract excerpt

DNA variants in a 31-kb region of the human major histocompatibility complex, encompassing the tumor necrosis factor (TNF) gene cluster, were surveyed by direct sequencing of 283 unrelated individuals from six Chinese populations. A total of 273 polymorphic sites were identified, with nearly half of them novel. We observed an excess of rare variants and negative values of selection tests of the region, implying...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to China

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to TNF gene

Share to Haplotypes

Share to Multigene Family

Share to Polymorphism, Single Nucleotide

Share to Recombination, Genetic

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 20505680
DOI: 10.1038/jhg.2010.33

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nucleotide polymorphism of the TNF gene cluster in six Chinese populations.PMID 20505680Read ↗

The evolution and diversity of TNF block haplotypes in European, Asian and Australian Aboriginal populations.Semantic proximity Read ↗

Polymorphisms at the TNF locus in Chinese Han population.Semantic proximity Read ↗

TNF-alpha promoter single nucleotide polymorphisms are markers of human ancestry.Semantic proximity Read ↗

Distribution of seven polymorphic markers and haplotypes within the human TNF gene cluster in Koreans.Semantic proximity Read ↗

Three TNFalpha single nucleotide polymorphisms in the Japanese population.Semantic proximity Read ↗

Highly informative typing of the human TNF locus using six adjacent polymorphic markers.Semantic proximity Read ↗

Genotype frequency and F ST analysis of polymorphisms in immunoregulatory genes in Chinese and Caucasian populations.Semantic proximity Read ↗

High-Density SNP genotyping defines 17 distinct haplotypes of the TNF block in the Caucasian population: implications for haplotype tagging.Semantic proximity Read ↗

Post-genomics and the neutral theory: variation and conservation in the tumor necrosis factor-alpha promoter.Semantic proximity Read ↗

A novel gene variation of TNFalpha associated with ankylosing spondylitis: a reconfirmed study.Semantic proximity Read ↗

Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-alpha gene promoter.Semantic proximity Read ↗

Identification of single nucleotide polymorphisms in the tumor necrosis factor (TNF) and TNF receptor superfamily in the Korean population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.