Article
TNF block haplotypes associated with conserved MHC haplotypes in European, Asian and Australian Aboriginal donors.
Tissue antigens - 1 Jul 2009
Valente F P, Tan C, Phipps M, Witt C S, Kaur G, Gut I, Allcock R, Price P
Abstract excerpt
Associations between major histocompatibility complex (MHC) ancestral haplotypes (AHs) and immunopathological diseases are traditionally ascribed to human leukocyte antigen (HLA) class I or class II alleles. However, polymorphisms in TNF and nearby genes in the central MHC can influence risk. We have defined TNF block haplotypes in Asian, European and Australian Aboriginal donors and shown conservation of TNF...
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