Article
TNF haplotypes in a Southern African population resemble those seen in Caucasians and Asians.
Genes and immunity - 1 Jun 2013
Chew C S N, Wadley A L, Lombard Z, Kamerman P R, Price P
Abstract excerpt
Haplotypes spanning the tumor necrosis factor (TNF) gene block in the central major histocompatibility complex were defined in a Southern African population using 31 single-nucleotide polymorphisms. Twenty haplotypes accounted for 91.8% of the cohort. The haplotypes matched those described previously in Caucasian and Asian populations, supporting the hypothesis that TNF block haplotypes are ancient and highly...
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