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Article

Enhanced Molecular Aging in Late-Life Depression: the Senescent-Associated Secretory Phenotype.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Jan 2017

Diniz Breno Satler, Reynolds Charles F, Sibille Etienne, Lin Chien-Wei, Tseng George, Lotrich Francis, Aizenstein Howard J, Butters Meryl A

Abstract excerpt

OBJECTIVE: This study aims to investigate whether a systemic molecular pattern associated with aging (senescent-associated secretory phenotype [SASP]) is elevated in adults with late-life depression (LLD), compared with never-depressed elderly comparison participants. DESIGN: Cross-sectional study. PARTICIPANTS: We included 111 older adults (80 with LLD and 31 comparison participants) in this study. MEASUREMENT:...

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Identifiers

PMID: 27856124
DOI: 10.1016/j.jagp.2016.08.018
PMCID: PMC5164865

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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