Article

Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia

2019-04-28

Abstract excerpt

<h4>Objective</h4> Late-life depression is associated with an increased risk for dementia, but our knowledge of the molecular mechanisms underlying this association is limited. Hence, the authors investigated whether microRNAs, important post-transcriptional regulators of gene expression, contribute to this association. <h4>Method</h4> Late-life depressive symptoms were assessed annually in 300 non-demented part...

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Literature Corpus work: 3edc1e3c-0545-505f-aa1e-b5bd931cd542
DOI: 10.1101/620815

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