Article
DNA hypermethylation of a selective gene panel as a risk marker for colon cancer in patients with ulcerative colitis.
International journal of molecular medicine - 1 May 2013
Kim Tae-Oh, Park Jongha, Kang Myoung Joo, Lee Sang Heon, Jee Sam Ryong, Ryu Dong Yup, Yang Kwangmo, Yi Joo Mi
Abstract excerpt
Patients with inflammatory bowel disease (IBD) which includes ulcerative colitis (UC) and Crohn's disease (CD) of the colon are at risk of developing colorectal cancer (CRC). Here, we analyzed the methylation status of selected genes as a risk marker in UC patients. We assessed methylation frequency of 4 genes [secreted frizzled-related protein 1 (SFRP1), transcription elongation regulator 1-like (TCERG1L),...
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