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DNA methylation analysis of SFRP2, GATA4/5, NDRG4 and VIM for the detection of colorectal cancer in fecal DNA

4 Aug 2014

Abstract excerpt

Aberrantly methylated genes are increasingly being established as biomarkers for the detection of colorectal cancer (CRC). In the present study, the methylation levels of the secreted frizzled‑related protein gene 2 (SFRP2), GATA binding protein 4/5 (GATA4/5), N‑Myc downstream‑regulated gene 4 (NDRG4) and vimentin (VIM) promoters were evaluated for their use as markers in the noninvasive detection of CRC....

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Share to Colorectal Cancer Screening and Detection
Share to Epigenetics and DNA Methylation
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Identifiers

PMID: 25202404
DOI: 10.3892/ol.2014.2413

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