Article
Detection of DNA hypermethylation in sera of patients with Crohn's disease.
Molecular medicine reports - 1 Feb 2014
Bae Jin-Han, Park Jongha, Yang Kwang Mo, Kim Tae-Oh, Yi Joo Mi
Abstract excerpt
Mounting evidence suggests that inflammatory bowel disease (IBD) is caused by genetic predisposition of various genes as well as an abnormal interaction with environmental factors, resulting in epigenetic alterations. It has become evident that epigenetic factors play a significant contributory role during disease development. Additionally, DNA methylation has been reported to be correlated with the development...
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