Article
Genome-wide DNA Methylation in Treatment-naïve Ulcerative Colitis.
Journal of Crohn's & colitis - 15 Nov 2018
Taman Hagar, Fenton Christopher G, Hensel Inga V, Anderssen Endre, Florholmen Jon, Paulssen Ruth H
Abstract excerpt
BACKGROUND AND AIMS: The aim of this study was to investigate the genome-wide DNA methylation status in treatment-naïve ulcerative colitis [UC], and to explore the relationship between DNA methylation patterns and gene expression levels in tissue biopsies from a well-stratified treatment-naïve UC patient group. METHODS: Mucosal biopsies from treatment-naïve patients [n = 10], and a healthy control group [n = 11]...
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