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Article

Comprehensive DNA Methylation Profiling of Inflammatory Mucosa in Ulcerative Colitis.

Inflammatory bowel diseases - 1 Jan 2017

Tahara Tomomitsu, Hirata Ichiro, Nakano Naoko, Nagasaka Mitsuo, Nakagawa Yoshihito, Shibata Tomoyuki, Ohmiya Naoki

Abstract excerpt

INTRODUCTION: Aberrant DNA methylation frequently occurs in the inflammatory mucosa in ulcerative colitis (UC) and is involved in UC-related tumorigenesis. We performed comprehensive DNA methylation profiling of the promoter regions of the inflamed rectal mucosae of patients with UC. DESIGN: The methylation status of the promoter CpG islands (CGIs) of 45 cancer/inflammation or age-related candidate genes and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27930411
DOI: 10.1097/MIB.0000000000000990

Genes

DPYS
GSTP1
SOX11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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