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Article

MGMT-B gene promoter hypermethylation in patients with inflammatory bowel disease - a novel finding.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Mokarram Pooneh, Kavousipour Soudabeh, Sarabi Mostafa Moradi, Mehrabani Golnosh, Fahmidehkar Mohammad Ali, Shamsdin Seyedeh Azra, Alipour Abbas, Naini Mahvash Alizade

Abstract excerpt

Inflammatory bowel disease (IBD) is a disease strongly associated with colorectal cancer (CRC) as a well-known precancerous condition. Alterations in DNA methylation and mutation in K-ras are believed to play an early etiopathogenic role in CRC and may also an initiating event through deregulation of molecular signaling. Epigenetic silencing of APC and SFRP2 in the WNT signaling pathway may also be involved in...

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Source

Identifiers

PMID: 25773792
DOI: 10.7314/apjcp.2015.16.5.1945

Genes

MGMT
SFRP2
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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