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Article

Epigenome-Wide Analysis of DNA Methylation Reveals a Rectal Cancer-Specific Epigenomic Signature

16 Aug 2016

Abstract excerpt

AIM: The aim of the present study is to address a genome-wide search for novel methylation biomarkers in the rectal cancer (RC), as only scarce information on methylation profile is available. MATERIALS & METHODS: We analyzed methylation status in 25 pairs of RC and adjacent healthy mucosa using the Illumina Human Methylation 450 BeadChip. RESULTS: We found significantly aberrant methylation in 33 genes. After...

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PMID: 27529132
DOI: 10.2217/epi-2016-0044

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