Article
DNA methylation in inflammatory bowel disease and beyond.
World journal of gastroenterology - 28 Aug 2013
Low Daren, Mizoguchi Atsushi, Mizoguchi Emiko
Abstract excerpt
Inflammatory bowel disease (IBD) is a consequence of the complex, dysregulated interplay between genetic predisposition, environmental factors, and microbial composition in the intestine. Despite a great advancement in identifying host-susceptibility genes using genome-wide association studies (GWAS), the majority of IBD cases are still underrepresented. The immediate challenge in post-GWAS era is to identify...
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