Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ERK phosphorylation is not increased in papillary thyroid carcinomas with BRAF(V600E) mutation compared to that of corresponding normal thyroid tissues.

Endocrine research - 1 Jan 2013

Kim Sun Wook, Kim Hee Kyung, Lee Ji In, Jang Hye Won, Choe Jun-Ho, Kim Jung-Han, Kim Jee Soo, Hur Kyu Yeon, Kim Jae Hyeon, Chung Jae Hoon

Abstract excerpt

BACKGROUND: An association between a BRAF(V600E) mutation and upregulation of mitogen-activated protein kinase (MAPK) pathways in human papillary thyroid carcinoma (PTC) tissues has not been demonstrated well outside of in vitro studies. The aims of this study were to evaluate the activation status of extracellular signal-regulated kinase 1/2 (ERK1/2) in human PTCs with BRAF(V600E) mutations compared to that of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma, Papillary
Share to Carcinoma

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carcinoma, Papillary

Share to Mitogen-Activated Protein Kinases

Share to Proto-Oncogene Proteins B-raf

Share to Thyroid Cancer, Papillary

Share to Thyroid Gland

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 23544999
DOI: 10.3109/07435800.2012.723292

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ERK phosphorylation is not increased in papillary thyroid carcinomas with BRAF(V600E) mutation compared to that of corresponding normal thyroid tissues.PMID 23544999Read ↗

Lack of association between BRAF V600E mutation and mitogen-activated protein kinase activation in papillary thyroid carcinoma.Semantic proximity Read ↗

BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications.Semantic proximity Read ↗

BRAF mutations in papillary thyroid carcinoma and emerging targeted therapies (review).Semantic proximity Read ↗

BRAF mutation in papillary thyroid cancer: pathogenic role, molecular bases, and clinical implications.Semantic proximity Read ↗

BRAF V600E Mutation Lacks Association with Poorer Clinical Prognosis in Papillary Thyroid Carcinoma.Semantic proximity Read ↗

Role of BRAF in thyroid oncogenesis.Semantic proximity Read ↗

BRAF V600E mutation in papillary thyroid carcinoma: significant association with node metastases and extra thyroidal invasion.Semantic proximity Read ↗

The role of BRAF in the pathogenesis of thyroid carcinoma.Semantic proximity Read ↗

No correlation between BRAF<sup>V600E</sup> mutation and clinicopathological features of papillary thyroid carcinomas in TaiwanSemantic proximity Read ↗

The Frequency and Clinical Implications of the BRAFV600EMutation in Papillary Thyroid Cancer Patients in Korea Over the Past Two DecadesSemantic proximity Read ↗

Multiple proliferation-survival signalling pathways are simultaneously active in BRAF V600E mutated thyroid carcinomas.Semantic proximity Read ↗

Targeting of the BRAF gene in papillary thyroid carcinoma (review).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.