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Article

BRAF V600E mutation in papillary thyroid carcinoma: significant association with node metastases and extra thyroidal invasion.

Endocrine pathology - 1 Jun 2012

Chakraborty Avik, Narkar Archana, Mukhopadhyaya Rita, Kane Shubhada, D'Cruz Anil, Rajan M G R

Abstract excerpt

B-Raf (BRAF) is the strongest activator in the downstream of MAP kinase signaling. The somatic point mutation of BRAF gene (V600E) is the most common and specific event in papillary thyroid carcinoma (PTC). However, its prevalence is variable among different studies and its association with clinico-pathological features is controversial. This study tests the prevalence of BRAF (V600E)...

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Share to Adenocarcinoma, Follicular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22105775
DOI: 10.1007/s12022-011-9184-5

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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BRAF V600E mutation in papillary thyroid carcinoma: significant association with node metastases and extra thyroidal invasion.PMID 22105775Read ↗

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