Article
Targeting of the BRAF gene in papillary thyroid carcinoma (review).
Oncology reports - 1 Oct 2009
Li Yaqiong, Nakamura Misa, Kakudo Kennichi
Abstract excerpt
Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy and includes several histological variants. Patients suffering from PTC usually have a good outcome. However, a group of PTC patients still encounter high rates of recurrence and mortality. The BRAFV600E mutation is the most common genetic alteration identified in PTC, ranging from 29 to 83%, with the average rate about 40%. To date,...
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